Title:
Mosaicism in the mouse trophectoderm
Authors:
Cruz, Yolanda P.
Abstract:
The issue of mosaicism in the mouse trophectoderm is examined by reviewing two sets of evidence: one arguing for a mosaic, the other for a non-mosaic character. Evidence for mosaicism includes documented cellular contribution from the inner cell mass to the trophectoderm, and data that reveal the gradual pace of the allocation process that separates the inner cell mass and trophectoderm lineages. Evidence suggesting a non-mosaic character for the trophectoderm is based on the polarization process undergone by exterior cells in the eight-celled embryo, the heritability of the changes brought about by this process, and the formation of gap junctions between the resulting apolar, trophectoderm progenitor cells. Since inner-cell-mass cells are developmentally labile, spatially heterogeneous and translocate to the polar trophectoderm, it is concluded that the polar trophectoderm is a mosaic tissue.
Citation:
Cruz, Y.P. 1990. "Mosaicism in the mouse trophectoderm." Tissue and Cell 22(2): 103-111.
Publisher:
Elsevier
DATE ISSUED:
1990-01
Department:
Biology
Type:
Article
PUBLISHED VERSION:
10.1016/0040-8166(90)90014-Z
Additional Links:
http://linkinghub.elsevier.com/retrieve/pii/004081669090014Z
PERMANENT LINK:
http://hdl.handle.net/11282/600484

Full metadata record

DC FieldValue Language
dc.contributor.authorCruz, Yolanda P.en
dc.date.accessioned2016-03-02T14:38:22Zen
dc.date.available2016-03-02T14:38:22Zen
dc.date.issued1990-01en
dc.identifier.citationCruz, Y.P. 1990. "Mosaicism in the mouse trophectoderm." Tissue and Cell 22(2): 103-111.en
dc.identifier.issn0040-8166en
dc.identifier.urihttp://hdl.handle.net/11282/600484en
dc.description.abstractThe issue of mosaicism in the mouse trophectoderm is examined by reviewing two sets of evidence: one arguing for a mosaic, the other for a non-mosaic character. Evidence for mosaicism includes documented cellular contribution from the inner cell mass to the trophectoderm, and data that reveal the gradual pace of the allocation process that separates the inner cell mass and trophectoderm lineages. Evidence suggesting a non-mosaic character for the trophectoderm is based on the polarization process undergone by exterior cells in the eight-celled embryo, the heritability of the changes brought about by this process, and the formation of gap junctions between the resulting apolar, trophectoderm progenitor cells. Since inner-cell-mass cells are developmentally labile, spatially heterogeneous and translocate to the polar trophectoderm, it is concluded that the polar trophectoderm is a mosaic tissue.en
dc.language.isoen_USen
dc.publisherElsevieren
dc.identifier.doi10.1016/0040-8166(90)90014-Zen
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/004081669090014Zen
dc.subject.departmentBiologyen_US
dc.titleMosaicism in the mouse trophectodermen_US
dc.typeArticleen
dc.identifier.journalTissue and Cellen
dc.subject.keywordMosaicismen_US
dc.subject.keywordCell allocationen_US
dc.subject.keywordMouse embryoen_US
dc.identifier.volume22en_US
dc.identifier.issue2en_US
dc.identifier.startpage103en_US
dc.rightsArchived with thanks to Tissue and Cellen
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