Uterine histology of the dasyurid marsupial, Antechinus Stuartii: relationship with differentiation of the embryo

Title:
Uterine histology of the dasyurid marsupial, Antechinus Stuartii: relationship with differentiation of the embryo
Authors:
Cruz, Yolanda P.; Selwood, Lynne
Abstract:
Uterine samples from Antechinus stuartii on days 1, 4, 6, 8, 11, 13, 15, 18, 21 and 23 after ovulation were examined histologically. Animals were pregnant, nonpregnant and unmated, or nonpregnant and mated but found to have only unfertilized eggs on autopsy. The histological parameters used were thickness of the myometrium, endometrial stroma, and endometrial epithelium, and density of uterine stromal glands and of lymphocytes at the endometrial basal lamina. Overall, the fluctuation patterns of these parameters were superficially similar between pregnant and nonpregnant animals (mated or unmated). However, statistically significant differences were detected between pregnant and unmated nonpregnant animals in every parameter examined at nearly every time point except day 13. Comparison of these results with known data on embryonic stages, corpus luteum development and plasma progesterone concentrations revealed that the gravid uterus underwent histological changes co-incident with changes in both progesterone concentration and developmental delay or embryonic arrest. It was concluded that the uterus mediates progesterone-driven changes in embryonic developmental rate. Although determination of number of lymphocytes provided inconclusive evidence of cellular immunity against embryos, the possibility that embryonic signalling to the uterus occurs is discussed.
Citation:
Cruz, Y.P., and L. Selwood. 1993. "Uterine histology of the dasyurid marsupial, Antechinus Stuartii: relationship with differentiation of the embryo." Reproduction 99(1): 237-242.
Publisher:
BioScientifica / Society for Reproduction and Fertility
DATE ISSUED:
1993-09-01
Department:
Biology
Type:
Article
PUBLISHED VERSION:
10.1530/jrf.0.0990237
Additional Links:
http://www.reproduction-online.org/cgi/doi/10.1530/jrf.0.0990237
PERMANENT LINK:
http://hdl.handle.net/11282/600463

Full metadata record

DC FieldValue Language
dc.contributor.authorCruz, Yolanda P.en
dc.contributor.authorSelwood, Lynneen
dc.date.accessioned2016-03-01T15:47:12Zen
dc.date.available2016-03-01T15:47:12Zen
dc.date.issued1993-09-01en
dc.identifier.citationCruz, Y.P., and L. Selwood. 1993. "Uterine histology of the dasyurid marsupial, Antechinus Stuartii: relationship with differentiation of the embryo." Reproduction 99(1): 237-242.en
dc.identifier.issn1470-1626en
dc.identifier.urihttp://hdl.handle.net/11282/600463en
dc.description.abstractUterine samples from Antechinus stuartii on days 1, 4, 6, 8, 11, 13, 15, 18, 21 and 23 after ovulation were examined histologically. Animals were pregnant, nonpregnant and unmated, or nonpregnant and mated but found to have only unfertilized eggs on autopsy. The histological parameters used were thickness of the myometrium, endometrial stroma, and endometrial epithelium, and density of uterine stromal glands and of lymphocytes at the endometrial basal lamina. Overall, the fluctuation patterns of these parameters were superficially similar between pregnant and nonpregnant animals (mated or unmated). However, statistically significant differences were detected between pregnant and unmated nonpregnant animals in every parameter examined at nearly every time point except day 13. Comparison of these results with known data on embryonic stages, corpus luteum development and plasma progesterone concentrations revealed that the gravid uterus underwent histological changes co-incident with changes in both progesterone concentration and developmental delay or embryonic arrest. It was concluded that the uterus mediates progesterone-driven changes in embryonic developmental rate. Although determination of number of lymphocytes provided inconclusive evidence of cellular immunity against embryos, the possibility that embryonic signalling to the uterus occurs is discussed.en
dc.language.isoen_USen
dc.publisherBioScientifica / Society for Reproduction and Fertilityen
dc.identifier.doi10.1530/jrf.0.0990237en
dc.relation.urlhttp://www.reproduction-online.org/cgi/doi/10.1530/jrf.0.0990237en
dc.subject.departmentBiologyen_US
dc.titleUterine histology of the dasyurid marsupial, Antechinus Stuartii: relationship with differentiation of the embryoen_US
dc.typeArticleen
dc.identifier.journalReproductionen
dc.identifier.volume99en_US
dc.identifier.issue1en_US
dc.identifier.startpage237en_US
dc.rightsArchived with thanks to Reproductionen
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