Tactics and Strategies for Managing Ebola Outbreaks and the Salience of Immunization

Title:
Tactics and Strategies for Managing Ebola Outbreaks and the Salience of Immunization
Authors:
Getz, Wayne M.; Gonzalez, Jean-Paul; Salter, Richard; Bangura, James; Carlson, Colin; Coomber, Moinya; Dougherty, Eric; Kargbo, David; Wolfe, Nathan D.; Wauquier, Nadia
Abstract:
We present a stochastic transmission chain simulation model for Ebola viral disease (EVD) in West Africa, with the salutary result that the virus may be more controllable than previously suspected. The ongoing tactics to detect cases as rapidly as possible and isolate individuals as safely as practicable is essential to saving lives in the current outbreaks in Guinea, Liberia, and Sierra Leone. Equally important are educational campaigns that reduce contact rates between susceptible and infectious individuals in the community once an outbreak occurs. However, due to the relatively low Ro of Ebola (around 1.5 to 2.5 next generation cases are produced per current generation case in naïve populations), rapid isolation of infectious individuals proves to be highly efficacious in containing outbreaks in new areas, while vaccination programs, even with low efficacy vaccines, can be decisive in curbing future outbreaks in areas where the Ebola virus is maintained in reservoir populations.
Citation:
Wayne M. Getz, Jean-Paul Gonzalez, Richard Salter, et al. 2015. “Tactics and Strategies for Managing Ebola Outbreaks and the Salience of Immunization.” Computational and Mathematical Methods in Medicine 2015, Article ID 736507.
Publisher:
Hindawi Publishing Corporation
DATE ISSUED:
2015-01-12
Department:
Computer Science
Type:
Article
PUBLISHED VERSION:
10.1155/2015/736507
PERMANENT LINK:
http://hdl.handle.net/11282/582287

Full metadata record

DC FieldValue Language
dc.contributor.authorGetz, Wayne M.en
dc.contributor.authorGonzalez, Jean-Paulen
dc.contributor.authorSalter, Richarden
dc.contributor.authorBangura, Jamesen
dc.contributor.authorCarlson, Colinen
dc.contributor.authorCoomber, Moinyaen
dc.contributor.authorDougherty, Ericen
dc.contributor.authorKargbo, Daviden
dc.contributor.authorWolfe, Nathan D.en
dc.contributor.authorWauquier, Nadiaen
dc.date.accessioned2015-11-17T13:54:28Zen
dc.date.available2015-11-17T13:54:28Zen
dc.date.issued2015-01-12en
dc.identifier.citationWayne M. Getz, Jean-Paul Gonzalez, Richard Salter, et al. 2015. “Tactics and Strategies for Managing Ebola Outbreaks and the Salience of Immunization.” Computational and Mathematical Methods in Medicine 2015, Article ID 736507.en
dc.identifier.issn1748-670Xen
dc.identifier.urihttp://hdl.handle.net/11282/582287en
dc.description.abstractWe present a stochastic transmission chain simulation model for Ebola viral disease (EVD) in West Africa, with the salutary result that the virus may be more controllable than previously suspected. The ongoing tactics to detect cases as rapidly as possible and isolate individuals as safely as practicable is essential to saving lives in the current outbreaks in Guinea, Liberia, and Sierra Leone. Equally important are educational campaigns that reduce contact rates between susceptible and infectious individuals in the community once an outbreak occurs. However, due to the relatively low Ro of Ebola (around 1.5 to 2.5 next generation cases are produced per current generation case in naïve populations), rapid isolation of infectious individuals proves to be highly efficacious in containing outbreaks in new areas, while vaccination programs, even with low efficacy vaccines, can be decisive in curbing future outbreaks in areas where the Ebola virus is maintained in reservoir populations.en
dc.language.isoen_USen
dc.publisherHindawi Publishing Corporationen
dc.identifier.doi10.1155/2015/736507en
dc.subject.departmentComputer Scienceen_US
dc.titleTactics and Strategies for Managing Ebola Outbreaks and the Salience of Immunizationen_US
dc.typeArticleen
dc.identifier.journalComputational and Mathematical Methods in Medicineen
dc.identifier.volume2015en_US
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