Neuronal synaptobrevin promotes longevity in Drosophila photoreceptors

Title:
Neuronal synaptobrevin promotes longevity in Drosophila photoreceptors
Authors:
Haberman, Adam
Abstract:
Neurons have unique challenges relative to other cell types. Unlike most other cells, neurons must remain healthy and functional throughout the lifespan of an animal. Premature neuronal loss underlies many age-related neurodegenerative diseases, including Alzheimer and Parkinson diseases. Despite previous research aimed at understanding the mechanisms of age-related neurodegenerative diseases, little is known about the mechanisms that allow neurons to remain functional for the lifetime of a healthy animal. Understanding these cellular and biochemical processes is essential to promote healthful aging and reduce the severity of neurodegenerative disease. Here we discuss our recent identification of neuron-specific proteins that regulate endosome fusion events and the role of endosomes in maintaining healthy neurons.
Citation:
Haberman, Adam. 2012. Neuronal Synaptobrevin promotes longevity in Drosophila Photoreceptors. Communicative and Integrative Biology, (5)6: 620-622.
Publisher:
Landes Bioscience
DATE ISSUED:
2012
Department:
Biology
Type:
article
PUBLISHED VERSION:
10.4161/cib.21434
PERMANENT LINK:
http://hdl.handle.net/11282/309681

Full metadata record

DC FieldValue Language
dc.contributor.authorHaberman, Adamen_US
dc.date.accessioned2013-12-23T16:14:58Z-
dc.date.available2013-12-23T16:14:58Z-
dc.date.issued2012en
dc.identifier.citationHaberman, Adam. 2012. Neuronal Synaptobrevin promotes longevity in Drosophila Photoreceptors. Communicative and Integrative Biology, (5)6: 620-622.en_US
dc.identifier.issn1942-0889en_US
dc.identifier.urihttp://hdl.handle.net/11282/309681-
dc.description.abstractNeurons have unique challenges relative to other cell types. Unlike most other cells, neurons must remain healthy and functional throughout the lifespan of an animal. Premature neuronal loss underlies many age-related neurodegenerative diseases, including Alzheimer and Parkinson diseases. Despite previous research aimed at understanding the mechanisms of age-related neurodegenerative diseases, little is known about the mechanisms that allow neurons to remain functional for the lifetime of a healthy animal. Understanding these cellular and biochemical processes is essential to promote healthful aging and reduce the severity of neurodegenerative disease. Here we discuss our recent identification of neuron-specific proteins that regulate endosome fusion events and the role of endosomes in maintaining healthy neurons.en_US
dc.language.isoen_USen_US
dc.publisherLandes Bioscienceen_US
dc.identifier.doi10.4161/cib.21434-
dc.subject.departmentBiologyen_US
dc.titleNeuronal synaptobrevin promotes longevity in Drosophila photoreceptorsen_US
dc.typearticleen_US
dc.identifier.journalCommunicative and Integrative Biologyen_US
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